Rosh Psychiatry Board Practice Exam 2025 - Free Psychiatry Board Practice Questions and Study Guide

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Which medication class is usually prescribed to treat Generalized Anxiety Disorder (GAD)?

Benzodiazepines

Selective Serotonin Reuptake Inhibitors (SSRIs)

Selective Serotonin Reuptake Inhibitors (SSRIs) are commonly prescribed to treat Generalized Anxiety Disorder (GAD) due to their efficacy in managing anxiety symptoms and their favorable side effect profile compared to other classes of medications. SSRIs work by increasing the levels of serotonin in the brain, a neurotransmitter that plays a key role in mood regulation. Clinical guidelines frequently recommend SSRIs as the first-line treatment for GAD because they are effective for both anxiety and associated depressive symptoms.

They offer a non-sedative option that helps reduce anxiety without the risk of dependency associated with benzodiazepines, making them more suitable for long-term management of GAD. SSRIs have been shown to improve overall function and quality of life for individuals with anxiety disorders.

While benzodiazepines can provide immediate relief for acute anxiety symptoms, they are not preferred for GAD because of their potential for dependence and withdrawal issues. Tricyclic antidepressants can also be effective but are often used less frequently due to their side effects. Stimulant medications, on the other hand, are not indicated for anxiety disorders and may exacerbate anxiety symptoms. Hence, SSRIs remain the primary medication class for treating Generalized Anxiety Disorder.

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Tricyclic antidepressants

Stimulant medications

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